1 Gulfport (8-2) at Biloxi (8-2) – Two traditional coast powerhouses at the top of their game.
2 Pearl (6-4) at Brandon (7-4) – Must win for both teams.
3 Starkville (9-2) at Clinton (5-5) – Clinton vies for playoffs.
4 Warren Central (6-4) at South Panola (10-1) – South Panola Tunes up for the playoffs.
5 Oxford (9-1) at Tupelo (7-3) – The battle for Lee County.
6 Provine (9-2) at Ridgeland (7-3) – Provine makes a playoff statement.
7 Picayune (10-0) at Wayne County (8-2) – Does Picayune even slow down?
8 Parklane (6-5) at Oak Forest (7-4) – MAIS 6A round one.
9 Winona (8-2) at Houston (7-3) – MAIS 3A Playoffs round one.
10 Rosa Fort (8-3) at Kosciusko (3-7) – MAIS 4A Playoffs round one.